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产品名称：avanti polar lipids/Huzzah® KLA, Human Serum Albumin / Kdo2 Lipid A Complex/1Ea/360500P-1EA

产品编号：360500P-1EA

市场价：¥5811.80

场地：美国(厂家直采)

产品分类：蛋白类>多肽>多肽合成>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$290.59

品牌： avanti polar lipids

公司：Avanti Lipids Polar, Inc.

公司分类：

商品介绍

Huzzah® KLA

Huzzah® KLA, Human Serum Albumin / Kdo2 Lipid A Complex

A new preparation of the saccharolipid glycan, Kdo₂-Lipid A (KLA), is a nearly homogeneous Re lipopolysaccharide (LPS) substructure with endotoxin activity equal to that of native LPS. KLA is comparable to LPS and its activity is reduced by >10³ in cells from TLR-4 deficient mice. The advantage of KLA over LPS is that it is a reproducible, defined natural product, and it can be detected by ESI/MS at the low concentrations used to stimulate animal cells. The purity of KLA should also facilitate the structural analysis of its complexes with signaling receptors, such as TLR-4/MD2.

New research* shows 1μg KLAinduces

the same response as 10μg LPS.

Perform experiments at half the cost of using LPS!Avanti’s new HSA lipid delivery system, Huzzah™, improves the cellular delivery of KLA through its conjugation with human serum albumin (HSA), a physiologically relevant carrier protein. This conjugate system improves the solubility of KLA in aqueous buffer.The Huzzah™ lipid delivery system is supplied as a lyophilized conjugate which can be directly and easily reconstituted in water or a buffer of choice and is ideal for studying the effects of poorly soluble bioactive molecules.Solubility: Reconstitute lyophilized conjugate in 2 mL of water or other aqueous buffer. This produces a stock solution of 85 - 110 µg/mL KLA*. A short sonication may be necessary to ensure complete dissolution. If necessary, filter sterilize the reconstituted conjugate prior to use in cell culture applications.*Exact concentration will vary from batch to batch. Refer to label for exact product concentration upon reconstitution as determined by mass spectrometric analysis.

Molar Ratio: KLA:albumin (1:1)Albumin Biological Characterization: microbial free; endotoxin < 1 IU/mLAlbumin Lipid Characterization: ~0.07g/L phospholipids; ~0.02 g/L sphingolipids; ~0.1 g/L fatty acids; and triglycerides and cholesterols below the limit of quantitation of 0.1 g/L and 0.05 g/L

品牌介绍

Avanti Polar Lipids.jpg

Avanti Polar Lipids公司是美国著名的磷脂类产品的生产商，该公司主要为各种制药厂和研究机构提供从毫克级到公斤级乃至吨级的磷脂类和甾体类中间体和试剂。为世界范围内的研究机构和制药公司提供 1000 种以上脂类产品，由于其产品的高纯度而享誉全球。40年来，Avanti Polar Lipids公司为世界各地的研究人员和制药公司提供脂类产品。公司的产品不仅范围日益扩大，其纯度之高也是无人能及。

Avanti Polar Lipids, Inc., has a long history of 50 years creating the highest purity lipids available. Our passion for high quality and unique products is only exceeded by our excellent reputation in the marketplace. Although we are known for our lipids, we are More than Lipids. We offer solutions for the entire product cycle…Research to Commercialization.

Avanti Polar Lipids公司的主要产品和服务包括：

（1）Research Products

Highest Purity Lipid Reagents

（2）cGMP Manufacturing

API & Contract Manufacturing

（3）Adjuvants

Immunotherapy & Vaccine Development

（4）Analytical Services

Lipid Analysis

（5）Lipidomics

Mass Spec Standards, Antibodies & Lipid Toolbox

（6）Formulations