Huzzah® LPA
Huzzah® LPA, Human Serum Albumin / Lyso Phosphatidic Acid Complex
Avanti’s new HSA lipid delivery system, Huzzah™, improves the cellular delivery of LPA through its conjugation with human serum albumin (HSA), a physiologically relevant carrier protein. This conjugate system eliminates the need for organic solvents, which are well-known to adversely affect viability and the phenotypic characteristics of cells.The Huzzah™ lipid delivery system is supplied as a lyophilized conjugate which can be directly and easily reconstituted in water or a buffer of choice and is ideal for studying the effects of poorly soluble bioactive molecules.Solubility: Reconstitute lyophilized conjugate in 5 mL of water or other aqueous buffer. This produces a stock solution of 120 - 200 µM LPA*. A short sonication may be necessary to ensure complete dissolution. If necessary, filter sterilize the reconstituted conjugate prior to use in cell culture applications.*Exact concentration will vary from batch to batch. Refer to label for exact product concentration upon reconstitution as determined by mass spectrometric analysis.
Molar Ratio: LPA:albumin (2:1)Albumin Biological Characterization: microbial free: endotoxin < 1 IU/mLAlbumin Lipid Characterization: ~0.07g/L phospholipids; ~0.02 g/L sphingolipids; ~0.1 g/L fatty acids; and triglycerides and cholesterols below the limit of quantitation of 0.1 g/L and 0.05 g/L
Avanti Polar Lipids公司是美国著名的磷脂类产品的生产商,该公司主要为各种制药厂和研究机构提供从毫克级到公斤级乃至吨级的磷脂类和甾体类中间体和试剂。为世界范围内的研究机构和制药公司提供 1000 种以上脂类产品,由于其产品的高纯度而享誉全球。40年来,Avanti Polar Lipids公司为世界各地的研究人员和制药公司提供脂类产品。公司的产品不仅范围日益扩大,其纯度之高也是无人能及。
Avanti Polar Lipids, Inc., has a long history of 50 years creating the highest purity lipids available. Our passion for high quality and unique products is only exceeded by our excellent reputation in the marketplace. Although we are known for our lipids, we are More than Lipids. We offer solutions for the entire product cycle…Research to Commercialization.
Avanti Polar Lipids公司的主要产品和服务包括:
(1)Research Products
Highest Purity Lipid Reagents
(2)cGMP Manufacturing
API & Contract Manufacturing
(3)Adjuvants
Immunotherapy & Vaccine Development
(4)Analytical Services
Lipid Analysis
(5)Lipidomics
Mass Spec Standards, Antibodies & Lipid Toolbox
(6)Formulations
Liposomes & Nanoparticles
(7)Equipment
Liposome Production Tools
(8)Custom Services
Synthesis & Beyond