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当前位置: 首页 > 产品中心 > Neutral Lipids > avanti polar lipids/1-stearoyl-2-docosahexaenoyl-sn-glycerol/800819C-10mg

avanti polar lipids/1-stearoyl-2-docosahexaenoyl-sn-glycerol/800819C-10mg

avanti polar lipids/1-stearoyl-2-docosahexaenoyl-sn-glycerol/800819C-10mg
  • avanti polar lipids/1-stearoyl-2-docosahexaenoyl-sn-glycerol/800819C-10mg
商品介绍
18:0-22:6 DG

18:0-22:6 DG

1-stearoyl-2-docosahexaenoyl-sn-glycerol

In biochemical signaling, diacylglycerol (DAG)functions as a second messenger signaling lipid, and is a product of the hydrolysis of the phospholipid PIP2 (phosphatidylinositolbisphosphate) by the enzyme phospholipase C (PLC) (a membrane-bound enzyme) that, through the same reaction, produces inositol trisphosphate (IP3). Although inositol trisphosphate (IP3) diffuses into the cytosol, DAG remains within the plasma membrane due to its hydrophobic properties. IP3 stimulates the release of calcium ions from the smooth endoplasmic reticulum, whereas DAG is a physiological activator of protein kinase C (PKC). The production of DAG in the membrane facilitates translocation of PKC from the cytosol to the plasma membrane. (See References)
Diacylglycerol mimicksthe effects ofthe tumor-promoting compounds phorbol esters.
Precaution:Since short chain Diacylglycerols mimic effects of the tumor-promoting phorbol diesters in a number of biological systems, extra care should be employed in their handling. Treatment of solutions, vessels and other articles with 1N NaOH before washing or discarding will destroy diacylglycerols.
Storage:
Diacylglycerols are conveniently stored in chloroform solutions in glass vials with teflon-lined caps at -20°C. Under these conditions acyl migration is minimal. Avoid plastic when handling chloroform solutions.
Delivery to cells:
Dry samples of diacylglycerol in chloroform, using a stream of nitrogen. Dissolve the residue in an appropriate volume of ethanol or DMSO, then dilute to the desired aqueous medium.
Effective concentration:
Most biological responses saturate at 20 to 250 µM sn-1,2-dioctanoylglycerol. Only sn-1,2 isomers appear to be active.
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Avanti Polar Lipids, Inc., has a long history of 50 years creating the highest purity lipids available. Our passion for high quality and unique products is only exceeded by our excellent reputation in the marketplace.

Although we are known for our lipids, we are More than Lipids. We offer solutions for the entire product cycle…Research to Commercialization.

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Avanti ships worldwide and encompasses all 8 divisions of our company including:

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We are here to help in any aspect of your research.

People do amazing things with our lipids…what will you do?


苏州蚂蚁淘生物科技有限公司是一家创新型高科技生物公司,以常规生物学实验外包与生物学试剂为基础,放眼于生命科学领域的前沿技术服务,公司技术骨干有着多年的生物学科研背景,毕业于国内外名牌大学,并且有着丰富的项目经验,了解国内外科研行情,我公司力求为每一个客户提专业、针对性的实验方案。我公司以技术服务为支点,和国内外多家生物试剂公司有着密切的业务往来.公司特色技术服务包括:抗体药物研发、噬菌体抗体库、蛋白表达与传化、抗体制备、高通量测序、组学研究、生物信息学分析与方法建立、基础分子生物学技术外包、化学中间体合成、原料药物研发、论文编写等。我公司秉承”诚信做人,认真做事,服务至上“,希望用我们的专业知识和项目经验为国内科研客户解决科研问题,祝您科研之路畅通无阻!


  • 为了研究一种利用纯化的组分重构细菌自动转运复合物,采用了Avanti Polar Lipids公司的phospholipids(磷脂),进行重构分析实验。
  • 为了研究液泡膜融合过程中约束操作的重要性,采用了Avanti Polar Lipids公司的16:0 DAG (1,2-dipalmitoyl-sn-glycerol),进行脂蛋白体制备实验。
  • 为了研究液泡膜融合过程中约束操作的重要性,采用了Avanti Polar Lipids公司的POPA (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate),进行脂蛋白体制备实验。
  • 为了研究液泡膜融合过程中约束操作的重要性,采用了Avanti Polar Lipids公司的POPS (1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine),进行脂蛋白体制备实验。
  • 为了研究液泡膜融合过程中约束操作的重要性,采用了Avanti Polar Lipids公司的Soy PI (L-alpha-phosphatidylinositol),进行脂蛋白体制备实验。
  • 为了研究液泡膜融合过程中约束操作的重要性,采用了Avanti Polar Lipids公司的POPE (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine),进行脂蛋白体制备实验。
  • 为了研究液泡膜融合过程中约束操作的重要性,采用了Avanti Polar Lipids公司的POPC (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine),进行脂蛋白体制备实验。
  • 为了研究一种保守的EMC蛋白复合物对磷酯转移的影响,采用了Avanti Polar Lipids公司的1-oleoyl-2-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sn-glycero-3-phosphoserine,进行Psd分析实验。
  • 为了研究大脂质囊泡中跨膜渗透压差对振荡相分离的影响,采用了Avanti Polar Lipids公司的Rhodamine-DPPE (lissamine rhodamine B 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine, triethylammonium salt),进行样品制备实验。
  • 为了研究大脂质囊泡中跨膜渗透压差对振荡相分离的影响,采用了Avanti Polar Lipids公司的POPC (egg) (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine),进行样品制备实验。
  • 为了研究一个胞质外膜羧酸盐通道家族蛋白的底物特异性,采用了Avanti Polar Lipids公司的egg phosphatidylcholine(蛋黄卵磷脂),进行脂质体膨胀分析实验。
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