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产品名称：avanti polar lipids/DSPE-PEG(2000)-DBCO/50mg/880229P-50mg

产品编号：880229P-50mg

市场价：¥14660.00

场地：美国(厂家直采)

产品分类：生化试剂>生物分子>脂类>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$733.00

品牌： avanti polar lipids

公司：Avanti Lipids Polar, Inc.

公司分类：

商品介绍

880229 | DSPE-PEG(2000)-DBCO

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[dibenzocyclooctyl(polyethylene glycol)-2000] (ammonium salt)

Info

DSPE-PEG(2000)-DBCO

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[dibenzocyclooctyl(polyethylene glycol)-2000] (ammonium salt)

Cu-free click chemistry with readily synthesized biarylazacyclooctynones. The reaction of azides with strained alkynes, such as cyclooctynes, readily forms a triazole product without the need for a toxic catalyst.

Refer also to DSPE-PEG Azide Avanti Number 880228

Representative Structure

The molecular weight and exact mass are averages based on the polydispersity of PEG.

Data

Hygroscopic

Yes

Light Sensitive

Molecular Formula

C₁₅₁H₂₇₉N₄O₅₆P (average MW due to polydispersity of PEG)

Percent Composition

C 58.93%, H 9.14%, N 1.82%, O 29.11%, P 1.01%

Purity

>99%

Stability

1 Year

Storage Temperature

-20°C

CAS Number

2052955-83-4 CAS Registry Number is a Registered Trademark of the American Chemical Society

FormulaWeight

3077.839

Exact Mass

3075.884

Synonyms

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl-amino(polyethylene glycol)-2000-N’-(succinylazadibenzocyclooctyne)] (ammonium salt)

Downloads

ChemDraw File
3D Structure
Structure
Safety Data Sheet

References

Wong P, Li L, Chea J, Hu W, Poku E, Ebner T, Bowles N, Wong JYC, Yazaki PJ, Sligar S, Shively JE. Antibody Targeted PET Imaging of 64Cu-DOTA-Anti-CEA PEGylated Lipid Nanodiscs in CEA Positive Tumors. Bioconjug Chem. 2020 Jan 30:10.1021/acs.bioconjchem.9b00854. doi: 10.1021/acs.bioconjchem.9b00854. Epub ahead of print. PMID: 31961138.

PubMed ID: 31961138

Umlauf BJ, Clark PA, Lajoie JM, Georgieva JV, Bremner S, Herrin BR, Kuo JS, Shusta EV. Identification of variable lymphocyte receptors that can target therapeutics to pathologically exposed brain extracellular matrix. Sci Adv. 2019 May 15;5(5):eaau4245. doi: 10.1126/sciadv.aau4245. eCollection 2019 May.

PubMed ID: 31106264

Gupta A, Shin JH, Lee MS, Park JY, Kim K, Kim JH, Suh M, Park CR, Kim YJ, Song MG, Jeong JM, Lee DS, Lee YS, Lee JS. Voxel-Based Dosimetry of Iron Oxide Nanoparticle-Conjugated 177Lu-Labeled Folic Acid Using SPECT/CT Imaging of Mice. Mol Pharm. 2019 Apr 1;16(4):1498-1506. doi: 10.1021/acs.molpharmaceut.8b01125. Epub 2019 Mar 18.

PubMed ID: 30821463

Jewett JC, Sletten EM, Bertozzi CR. Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones. J Am Chem Soc. 2010 Mar 24;132(11):3688-90. doi: 10.1021/ja100014q.

PubMed ID: 20187640

Whitehead SA, McNitt CD, Mattern-Schain SI, Carr AJ, Alam S, Popik VV, Best MD. Artificial Membrane Fusion Triggered by Strain-Promoted Alkyne-Azide Cycloaddition. Bioconjug Chem. 2017 Apr 19;28(4):923-932. doi: 10.1021/acs.bioconjchem.6b00578. Epub 2017 Mar 14.

PubMed ID: 28248084

Certificates of Analysis

Certificate of Analysis(Lot No. 880229P-100MG-A-013and 6308PLA013)
Certificate of Analysis(Lot No. 880229P-10MG-A-013and 6308PIA013)
Certificate of Analysis(Lot No. 880229P-25MG-A-013and 6308PJA013)
Certificate of Analysis(Lot No. 880229P-50MG-A-013and 6308PKA013)
Certificate of Analysis(Lot No. 880229P-10MG-A-014and 6308PIA014)
Certificate of Analysis(Lot No. 880229P-25MG-B-013and 6308PJB013)
Certificate of Analysis(Lot No. 880229P-50MG-B-013and 6308PKB013)
Certificate of Analysis(Lot No. 880229P-100MG-A-014and 6308PLA014)
Certificate of Analysis(Lot No. 880229P-25MG-A-014and 6308PJA014)
Certificate of Analysis(Lot No. 880229P-50MG-A-014and 6308PKA014)
Certificate of Analysis(Lot No. 880229P-10MG-B-014and 6308PIB014)
Certificate of Analysis(Lot No. 880229P-100MG-B-014and 6308PLB014)
Certificate of Analysis(Lot No. 880229P-10MG-C-014and 6308PIC014)
Certificate of Analysis(Lot No. 880229P-100MG-C-014and 6308PLC014)
Certificate of Analysis(Lot No. 880229P-25MG-A-015and 6308PJA015)
Certificate of Analysis(Lot No. 880229P-50MG-A-015and 6308PKA015)
Certificate of Analysis(Lot No. 880229P-25MG-B-015and 6308PJB015)
Certificate of Analysis(Lot No. 880229P-10MG-A-015and 6308PIA015)
Certificate of Analysis(Lot No. 880229P-10MG-C-015and 6308PIC015)
Certificate of Analysis(Lot No. 880229P-50MG-B-015and 6308PKB015)
Certificate of Analysis(Lot No. 880229P-50MG-C-015and 6308PKC015)
Certificate of Analysis(Lot No. 880229P-25MG-C-015and 6308PJC015)
Certificate of Analysis(Lot No. 880229P-50MG-D-015and 6308PKD015)
Certificate of Analysis(Lot No. 880229P-100MG-A-016and 6308PLA016)
Certificate of Analysis(Lot No. 880229P-100MG-B-016and 6308PLB016)
Certificate of Analysis(Lot No. 880229P-25MG-A-016and 6308PJA016)
Certificate of Analysis(Lot No. 880229P-10MG-B-016and 6308PIB016)
Certificate of Analysis(Lot No. 880229P-50MG-C-016and 6308PKC016)
Certificate of Analysis(Lot No. 880229P-25MG-B-016and 6308PJB016)

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品牌介绍

Avanti Polar Lipids.jpg

Avanti Polar Lipids公司是美国著名的磷脂类产品的生产商，该公司主要为各种制药厂和研究机构提供从毫克级到公斤级乃至吨级的磷脂类和甾体类中间体和试剂。为世界范围内的研究机构和制药公司提供 1000 种以上脂类产品，由于其产品的高纯度而享誉全球。40年来，Avanti Polar Lipids公司为世界各地的研究人员和制药公司提供脂类产品。公司的产品不仅范围日益扩大，其纯度之高也是无人能及。

Avanti Polar Lipids, Inc., has a long history of 50 years creating the highest purity lipids available. Our passion for high quality and unique products is only exceeded by our excellent reputation in the marketplace. Although we are known for our lipids, we are More than Lipids. We offer solutions for the entire product cycle…Research to Commercialization.

Avanti Polar Lipids公司的主要产品和服务包括：

（1）Research Products

Highest Purity Lipid Reagents

（2）cGMP Manufacturing

API & Contract Manufacturing

（3）Adjuvants

Immunotherapy & Vaccine Development

（4）Analytical Services

Lipid Analysis

（5）Lipidomics

Mass Spec Standards, Antibodies & Lipid Toolbox

（6）Formulations